Lindane can be toxic to the brain and other parts of the nervous system its use should be restricted to patients who have failed treatment with or cannot tolerate other medications that pose less risk. However, lindane is not recommended as a first-line therapy. Lindane shampoo is a prescription medication that can kill lice and lice eggs. These medications are safe and effective when used exactly according to the instructions in the package or on the label. These products are available over-the-counter without a prescription at a local drug store or pharmacy. A lice-killing lotion containing 1% permethrin or a mousse containing pyrethrins and piperonyl butoxide can be used to treat pubic (“crab”) lice.
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